Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNA1 | Q09470 | 7/20 | 0.43 |
| ▸ | KCNAB1 | Q14722 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478799 | 0.91 | MEN1 (0.60) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9480112 | 0.90 | MEN1 (0.48) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9478605 | 0.90 | MEN1 (0.48) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9478165 | 0.90 | MEN1 (0.48) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9478847 | 0.89 | MEN1 (0.47) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9478237 | 0.88 | TP53 (0.56) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL7983217 | 0.86 | KCNA1 (0.53) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9477595 | 0.84 | EPHX1 (0.47) | MEN1KMT2AKCNA1KCNAB1MAPT | |
| SCHEMBL9478381 | 0.84 | CA1 (0.46) | MEN1KMT2AKCNA1KCNAB1TP53 | |
| SCHEMBL9478784 | 0.83 | CA12 (0.49) | KCNA1KCNAB1TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262440-A | Treatment of neoplasms | ELI LILLY AND COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0546763-A1 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |