Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049718 | 0.93 | P2RX7 (0.46) | P2RX7ROCK2ROCK1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9478386 | 0.92 | P2RX7 (0.46) | P2RX7ROCK2ROCK1HTR2AHTR2C | |
| SCHEMBL9046682 | 0.88 | P2RX7 (0.45) | P2RX7ROCK2ROCK1CYP2D6 | |
| Hydrochloric Acid SCHEMBL9477135 | 0.87 | P2RX7 (0.45) | P2RX7ROCK2ROCK1CYP2D6HTR2A | |
| Hydrochloric Acid SCHEMBL9477689 | 0.85 | P2RX7 (0.44) | P2RX7ROCK2ROCK1CYP2D6 | |
| SCHEMBL6213580 | 0.84 | P2RX7 (0.68) | P2RX7ROCK2ROCK1NPY5R | |
| SCHEMBL9477054 | 0.82 | ADRA1A (0.58) | P2RX7NPY5RCYP2D6HTR7KCNA3 | |
| SCHEMBL9045900 | 0.81 | FLT3 (0.47) | P2RX7ROCK2ROCK1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9479252 | 0.81 | FLT3 (0.47) | P2RX7ROCK2ROCK1HTR2AHTR2C | |
| Fumaric Acid SCHEMBL9477409 | 0.80 | HTR2A (0.47) | P2RX7ROCK2ROCK1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208243-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-05-04 | — | — | US | disclosed |