Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162262 | 0.98 | HCAR2 (0.46) | HCAR2KDM4ENAPRTALOX15ALDH1A1 | |
| SCHEMBL31118151 | 0.98 | HCAR2 (0.46) | HCAR2KDM4ENAPRTALOX15ALDH1A1 | |
| SCHEMBL69399 | 0.83 | KDM4E (0.55) | HCAR2KDM4ENAPRTALOX15ALDH1A1 | |
| SCHEMBL27315955 | 0.77 | ALDH1A1 (0.34) | HCAR2KDM4ENAPRTALDH1A1TSHR | |
| SCHEMBL163537 | 0.77 | ADORA3 (0.48) | HCAR2KDM4ENAPRTALDH1A1TSHR | |
| SCHEMBL14764682 | 0.77 | HCAR2 (0.45) | HCAR2KDM4ENAPRTALOX15ALDH1A1 | |
| SCHEMBL9478486 | 0.76 | CA1 (0.32) | HCAR2KDM4ENAPRTALDH1A1HPGD | |
| SCHEMBL162261 | 0.74 | HCAR2 (0.46) | HCAR2KDM4ENAPRTALOX15ALDH1A1 | |
| SCHEMBL3037984 | 0.73 | TSHR (0.54) | HCAR2KDM4ENAPRTALOX15ALDH1A1 | |
| SCHEMBL20929039 | 0.73 | KDM4E (0.45) | HCAR2KDM4ENAPRTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238829-A | Hydroxylation of pyrazinecarboxylic acid(or salts) by Alcaligenes faecalis which can grow using picolinic acid(or salts) as sole source of carbon, nitrogen and energy | LONZA LTD. (CH) | 1993-08-24 | — | — | US | disclosed |