SCHEMBL9479686

SCHEMBL9479686

O=C(Nc1ccc(Nc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIRT1 Q96EB6 1/20 0.78
▸ MEN1 O00255 4/20 0.77
▸ KMT2A Q03164 4/20 0.77
▸ POLB P06746 3/20 0.77
▸ PTPN1 P18031 3/20 0.75
▸ NPC1 O15118 4/20 0.71
▸ RAB9A P51151 4/20 0.71
▸ KDM4E B2RXH2 2/20 0.71
▸ MAPT P10636 1/20 0.69
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ KCNK3 O14649 1/20 0.68
▸ KCNK9 Q9NPC2 1/20 0.68
▸ CACNA1B Q00975 1/20 0.67
▸ APBA1 Q02410 1/20 0.67
▸ CASP3 P42574 1/20 0.67
▸ SENP7 Q9BQF6 1/20 0.67
▸ CTDSP1 Q9GZU7 1/20 0.66
▸ TDP1 Q9NUW8 1/20 0.66
▸ HDAC2 Q92769 1/20 0.66
▸ HDAC8 Q9BY41 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480256 1.00 SIRT1 (0.78) SIRT1MEN1KMT2APOLBPTPN1
SCHEMBL18330583 0.98 PTPN1 (0.77) SIRT1MEN1KMT2APOLBPTPN1
N-Phenylbenzamide SCHEMBL8651257 0.98 SIRT1 (0.74) SIRT1MEN1KMT2APOLBPTPN1
SCHEMBL11124245 0.96 MEN1 (0.83) SIRT1MEN1KMT2APOLBPTPN1
SCHEMBL26953087 0.91 PTPN1 (0.88) SIRT1MEN1KMT2APOLBPTPN1
SCHEMBL126415 0.91 PTPN1 (0.87) SIRT1MEN1KMT2APOLBPTPN1
SCHEMBL24202631 0.91 SIRT1 (0.83) SIRT1MEN1KMT2APOLBPTPN1
N-Phenylbenzamide SCHEMBL31966 0.91 SIRT1 (0.83) SIRT1MEN1KMT2APOLBPTPN1
N-Phenylbenzamide SCHEMBL5402750 0.91 SIRT1 (0.83) SIRT1MEN1KMT2APOLBPTPN1
SCHEMBL14715847 0.89 PTPN1 (0.84) SIRT1MEN1KMT2APOLBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483326-A 2,6- bis- (p-aminophenyl oxygroup)-N- [(4- anilino-) phenyl] benzamide monomer and preparation method thereof ANYANG INST TECH 2019-11-22 — — CN claimed
CN-109369437-A Preparation method of antioxidant anti-aging agent N- (4-anilinophenyl) benzamide 连云港锐巴化工有限公司 2019-02-22 — — CN claimed
CN-114276270-A Synthesis method of compound with amido bond 湖北文理学院 2022-04-05 — — CN disclosed
CN-110483326-A 2,6- bis- (p-aminophenyl oxygroup)-N- [(4- anilino-) phenyl] benzamide monomer and preparation method thereof ANYANG INST TECH 2019-11-22 — — CN disclosed
CN-109369437-A Preparation method of antioxidant anti-aging agent N- (4-anilinophenyl) benzamide 连云港锐巴化工有限公司 2019-02-22 — — CN disclosed
CN-109369437-A Preparation method of antioxidant anti-aging agent N- (4-anilinophenyl) benzamide 连云港锐巴化工有限公司 2019-02-22 — — CN disclosed
CN-109369437-A Preparation method of antioxidant anti-aging agent N- (4-anilinophenyl) benzamide 连云港锐巴化工有限公司 2019-02-22 — — CN disclosed
WO-2014011663-A1 INHIBITORS OF BACTERIAL DIGUANYLATE CYCLASE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2014-01-16 — — WO disclosed
US-5210065-A A mixture of an aromatic amine, an oxidizer and an acid MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-05-11 — — US disclosed
EP-0479578-A1 Color-forming recording material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 — — EP disclosed
US-4386181-A CONJUGATED DIENE, N-/ANILINOPHENYL/ACRYLAMIDE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-05-31 — — US disclosed
EP-0009041-B1 PROCESS FOR PREPARING AROMATIC AMIDE ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-10-06 — — EP disclosed
US-4163015-A ANTIBACTERIAL AGENTS STERLING DRUG INC. (US) 1979-07-31 — — US disclosed
US-4138405-A BACTERICIDES STERLING DRUG INC. (US) 1979-02-06 — — US disclosed
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