SCHEMBL18330583

SCHEMBL18330583

O=C(Nc1ccc(Nc2ccc(NC(=O)c3ccccc3)cc2)cc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.77
NPC1 O15118 6/20 0.74
RAB9A P51151 6/20 0.74
MEN1 O00255 4/20 0.74
KMT2A Q03164 4/20 0.74
POLB P06746 2/20 0.74
SIRT1 Q96EB6 1/20 0.74
KDM4E B2RXH2 1/20 0.74
MAPT P10636 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
CACNA1B Q00975 1/20 0.69
APBA1 Q02410 1/20 0.69
PRMT1 Q99873 1/20 0.67
FFAR1 O14842 1/20 0.67
PGR P06401 1/20 0.67
JAK2 O60674 1/20 0.66
TYK2 P29597 1/20 0.66
SIRT2 Q8IXJ6 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480256 0.98 SIRT1 (0.78) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL9479686 0.98 SIRT1 (0.78) PTPN1NPC1RAB9AMEN1KMT2A
N-Phenylbenzamide SCHEMBL8651257 0.96 SIRT1 (0.74) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL11124245 0.94 MEN1 (0.83) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL126415 0.93 PTPN1 (0.87) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL18103163 0.91 NPC1 (0.88) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL14715824 0.91 NPC1 (0.88) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL11550249 0.91 MEN1 (0.68) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL29393952 0.89 JAK2 (0.86) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL26953087 0.89 PTPN1 (0.88) PTPN1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244882-A1 DISPLAY DEVICE AND MANUFACTURING METHOD OF DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-18 US disclosed
US-20230403920-A1 METHOD OF MANUFACTURING DISPLAY PANEL AND THE DISPLAY PANEL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-12-14 US disclosed
US-20230292544-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-09-14 US disclosed
US-20230276700-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-08-31 US disclosed
EP-3309851-B1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT NISSAN CHEMICAL CORP (JP) 2020-01-01 EP disclosed
US-20180163061-A1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-14 US disclosed
EP-3309851-A1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT Nissan Chemical Industries, Ltd. (JP) 2018-04-18 EP disclosed
WO-2016204079-A1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT 日産化学工業株式会社 2016-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276700-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SLC43A1, SLC7A5, SLCO4C1 PTPN1 4762/4885NPC1 1094/4885RAB9A 1214/4885
US-20180163061-A1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLC26A3 PTPN1 4270/4885NPC1 297/4885RAB9A 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.