Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP12 | P39900 | 5/20 | 0.41 |
| ▸ | MMP13 | P45452 | 5/20 | 0.41 |
| ▸ | MMP14 | P50281 | 5/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP16 | P51512 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203454 | 0.79 | HSD17B10 (0.39) | HTR6TSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL11572725 | 0.77 | CA2 (0.49) | KDM4EHPGD | |
| SCHEMBL6913555 | 0.77 | HTR6 (1.00) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| Biphenyl SCHEMBL28423764 | 0.76 | HTR6 (0.65) | HTR6NPSR1TSHRHTTGAA | |
| SCHEMBL9323437 | 0.76 | HTR6 (0.65) | HTR6HTTGAAPOLBKMT2A | |
| SCHEMBL8899315 | 0.75 | CYP1A2 (0.43) | HTR6NPSR1TSHRKMT2AALDH1A1 | |
| SCHEMBL23519060 | 0.75 | HTR6 (0.54) | HTR6NPSR1TSHRHTTABCC9 | |
| SCHEMBL8080841 | 0.75 | HTR6 (0.72) | HTR6NPSR1TSHRHTTGAA | |
| (Phenylsulfonyl)Benzene SCHEMBL11338108 | 0.75 | HTR6 (0.58) | HTR6NPSR1TSHRHTTPOLB | |
| SCHEMBL10730924 | 0.74 | HTR6 (0.49) | HTR6NPSR1HTTABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252647-A | Thermoplastic moulding materials based on polyphenylene ethers and polyamides | HUELS AKTIENGESELLSCHAFT (DE) | 1993-10-12 | — | — | US | disclosed |