Biphenyl

Biphenyl

SCHEMBL28423764

O=S(=O)(c1ccccc1)c1ccccc1Oc1ccccc1S(=O)(=O)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 6/20 0.65
MMP2 P08253 7/20 0.49
MMP9 P14780 7/20 0.49
MMP12 P39900 7/20 0.49
MMP13 P45452 7/20 0.49
MMP14 P50281 7/20 0.49
MMP1 P03956 6/20 0.49
MMP8 P22894 6/20 0.49
MMP16 P51512 6/20 0.49
MMP3 P08254 6/20 0.49
KMT2A Q03164 1/20 0.44
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
KDM4E B2RXH2 2/20 0.42
PKM P14618 1/20 0.42
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
CASP1 P29466 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1071653 0.91 HTR6 (0.59) HTR6MMP2MMP9MMP12MMP13
SCHEMBL9323437 0.85 HTR6 (0.65) HTR6MMP2MMP9MMP12MMP13
SCHEMBL7187841 0.84 HTR6 (0.64) HTR6MMP2MMP9MMP12MMP13
SCHEMBL10342789 0.84 HTR6 (0.65) HTR6MMP2MMP9MMP12MMP13
SCHEMBL10694219 0.81 HTR6 (0.56) HTR6KMT2AKDM4E
SCHEMBL28899852 0.80 AKR1B1 (0.44) HTR6MMP2MMP9MMP12MMP13
SCHEMBL9650276 0.79 HTR6 (0.58) HTR6MMP2MMP9MMP12MMP13
SCHEMBL6913555 0.78 HTR6 (1.00) HTR6MMP2MMP12MMP13MMP14
SCHEMBL11186053 0.78 MMP13 (0.61) HTR6MMP2MMP9MMP12MMP13
SCHEMBL5831246 0.78 HTR6 (0.56) HTR6MMP2MMP9MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111433254-B Preparation method of polyether ketone and prepared polyether ketone 韩华化学株式会社 2023-05-16 CN claimed
CN-111433254-A Method for producing polyetherketoneketones and polyetherketoneketones produced thereby 韩华化学株式会社 2020-07-17 CN claimed
CN-111433254-B Preparation method of polyether ketone and prepared polyether ketone 韩华化学株式会社 2023-05-16 CN disclosed
CN-110317322-B Particulate amine-functionalized polyaryletherketone polymers and copolymers thereof 塞特工业公司 2022-06-14 CN disclosed
CN-111433254-A Method for producing polyetherketoneketones and polyetherketoneketones produced thereby 韩华化学株式会社 2020-07-17 CN disclosed