Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518118 | 0.87 | LMNA (0.64) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL1453865 | 0.85 | LMNA (0.62) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL7848021 | 0.85 | KMT2A (0.51) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL11511978 | 0.84 | L3MBTL1 (0.61) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL12611654 | 0.84 | LMNA (0.61) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL5204883 | 0.83 | EPHX2 (0.66) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL10022852 | 0.83 | EPHX2 (0.66) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL11626154 | 0.83 | EPHX2 (0.66) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL5205374 | 0.83 | LMNA (0.63) | L3MBTL1LMNAKMT2AEPHX2MAPT | |
| SCHEMBL18562096 | 0.83 | LMNA (0.63) | L3MBTL1LMNAKMT2AEPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180730-A | Pyridylthiomethyl-Substituted Phenols, Antianaphylactic Agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-4933348-A | MEDICINES; ANTAGONISTS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS; PROPHYLAXIS AND TREATMENT OF ALLERGIC DISEASES | MASE TOSHIYASU (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4803211-A | Thiadizazole compounds as antagonists of SRS-A | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0214732-A2 | (Substituted benzyl)-thio heterocyclic compounds having a leukotriene-antagonist activity | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |
| US-4169720-A | 2-[4-(4-Chlorophenoxymethyl)-phenoxy]-propionic acid compounds as herbicides | CELAMERCK GMBH & CO. KG (DE) | 1979-10-02 | — | — | US | disclosed |