SCHEMBL5204883

SCHEMBL5204883

CCOC(=O)C(C)Oc1ccc(Cl)cc1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.66
KMT2A Q03164 1/20 0.61
LMNA P02545 3/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
PPARA Q07869 3/20 0.51
CYP1A2 P05177 2/20 0.51
ABCB11 O95342 1/20 0.51
CYP3A4 P08684 1/20 0.51
TSHR P16473 1/20 0.51
HTR2A P28223 1/20 0.51
PMP22 Q01453 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
POLB P06746 1/20 0.49
TDP1 Q9NUW8 2/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 2/20 0.47
PPARG P37231 2/20 0.47
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022852 1.00 EPHX2 (0.66) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL10964710 0.95 EPHX2 (0.62) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL11626154 0.92 EPHX2 (0.66) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL10703205 0.92 EPHX2 (0.59) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL11512491 0.91 EPHX2 (0.58) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL23605759 0.89 L3MBTL1 (0.76) EPHX2KMT2ALMNAL3MBTL1
SCHEMBL11510461 0.89 L3MBTL1 (0.76) EPHX2KMT2ALMNAL3MBTL1
SCHEMBL11516006 0.89 EPHX2 (0.56) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL28252830 0.87 EPHX2 (0.53) EPHX2KMT2ALMNAL3MBTL1PPARA
SCHEMBL21991473 0.86 EPHX2 (0.63) EPHX2KMT2ALMNAL3MBTL1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306591-A Method for generating phenoxycarboxylic acid by utilizing acid exchange 山东润博生物科技有限公司 2025-01-14 CN claimed
US-20070232492-A1 Herbicidal Composition ISHIHARA SANGYO KAISHA, LTD. (JP) 2007-10-04 US claimed
JP-1213201-A None JP disclosed
JP-56036403-A None JP disclosed
WO-2025103220-A1 PYRIDYL ALKOXY PYRIMIDINE COMPOUND AND USE THEREOF 青岛清原化合物有限公司 2025-05-22 WO disclosed
CN-119306591-A Method for generating phenoxycarboxylic acid by utilizing acid exchange 山东润博生物科技有限公司 2025-01-14 CN disclosed
CN-117645540-A Preparation method of chlorophenoxycarboxylate 山东润博生物科技有限公司 2024-03-05 CN disclosed
US-20220409566-A1 CCL5 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-12-29 US disclosed
US-20220142961-A1 CCL5 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-05-12 US disclosed
US-11318111-B2 CCL5 inhibitors LAPKO INC (US) 2022-05-03 US disclosed
US-20210196665-A1 CCL5 Inhibitors AFECTA PHARMACEUTICALS, INC. (US) 2021-07-01 US disclosed
US-4348534-A Preparation of 2-aryloxy-2-haloproptonic acid compounds BASF AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
US-4334914-A PRE-AND POSTEMERGENT APPLICATION NIHON NOHYAKU CO., LTD. (JP) 1982-06-15 US disclosed
US-4318731-A Δ2 -1,2,4-triazolin-5-one derivatives and herbicidal usage thereof NIHON NOHYAKU CO., LTD. (JP) 1982-03-09 US disclosed
EP-0034457-A1 Benzoate derivative, method of preparing the same and use thereof NIHON NOHYAKU CO., LTD. (JP) 1981-08-26 EP disclosed
JP-S5636403-A HERBICIDAL COMPOSITION HOKKO CHEM IND CO LTD 1981-04-09 JP disclosed
US-4226616-A A 3-ALKYL- OR -ALKYLOXYETHYLOXY-4-NITRO-2'-CHLORO-4'-TRIFLUOROMETHOXYDIPHENYL ETHER NIHON NOHYAKU CO., LTD. (JP) 1980-10-07 US disclosed
US-4157256-A Tetrahydrophthalimide and herbicide containing the same NIHON NOHYAKU CO. LTD. (JP) 1979-06-05 US disclosed
US-3961935-A Synergistic herbicidal composition comprising O-methyl or O-ethyl-O-(3-methyl-6-nitrophenyl)-N-secondary-butylphosphorothioamidate and a phenoxy-type herbicide SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-08 US disclosed
JP-S05636403-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142961-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 EPHX2 1344/4885KMT2A 4842/4885LMNA 4533/4885
US-20210196665-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 EPHX2 1344/4885KMT2A 4842/4885LMNA 4533/4885
US-20070232492-A1 Herbicidal Composition DDT, SPIN2B, CCNB3 EPHX2 2256/4885KMT2A 1270/4885LMNA 1003/4885
US-11318111-B2 CCL5 inhibitors CCL5, CCL11, CCR5 EPHX2 1344/4885KMT2A 4842/4885LMNA 4533/4885
US-20220409566-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 EPHX2 1344/4885KMT2A 4842/4885LMNA 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.