Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RPS27 | P42677 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757275 | 0.80 | KDM4E (0.42) | L3MBTL1GAAKDM4ESQORALDH1A1 | |
| SCHEMBL18691123 | 0.79 | MBOAT4 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL17316862 | 0.76 | LMNA (0.38) | KDM4EMAPK8MAPK9CYP11B1CYP11B2 | |
| SCHEMBL10371014 | 0.74 | L3MBTL1 (0.55) | L3MBTL1GAAMAPTTDP1KDM4E | |
| SCHEMBL9479813 | 0.73 | L3MBTL1 (0.36) | L3MBTL1GAAMAPTTDP1KDM4E | |
| SCHEMBL249966 | 0.71 | L3MBTL1 (0.49) | L3MBTL1GAAMAPTTDP1KDM4E | |
| SCHEMBL13836000 | 0.70 | — | — | |
| SCHEMBL25413494 | 0.69 | CFTR (0.34) | KDM4EKMT2AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL2230830 | 0.69 | L3MBTL1 (0.61) | L3MBTL1GAAMAPTTDP1KDM4E | |
| SCHEMBL1145995 | 0.69 | GAA (0.54) | L3MBTL1GAAMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |