SCHEMBL9480276

SCHEMBL9480276

Cc1ccc(S(=O)(=O)Nc2cccc(N(C)c3ccc(N(C)c4ccccc4)cc3)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA9 Q16790 1/20 0.65
ALDH1A1 P00352 6/20 0.63
LMNA P02545 5/20 0.58
MAPT P10636 2/20 0.58
GAA P10253 2/20 0.58
GFER P55789 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
MAPK1 P28482 1/20 0.58
MCL1 Q07820 1/20 0.58
FFAR1 O14842 2/20 0.56
CDK1 P06493 1/20 0.56
CCNB1 P14635 1/20 0.56
CCNA2 P20248 1/20 0.56
CDK2 P24941 1/20 0.56
CDK7 P50613 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479500 0.91 ALDH1A1 (0.74) ALDH1A1LMNAMAPTGAATDP1
SCHEMBL9480055 0.84 MEN1 (0.60) ALDH1A1LMNAMAPTGAAMEN1
SCHEMBL9001673 0.82 TCF4 (0.59) CA12CA1CA2CA9ALDH1A1
SCHEMBL14877794 0.82 CA12 (0.76) CA12CA1CA2CA9ALDH1A1
SCHEMBL9480275 0.81 ALDH1A1 (0.52) ALDH1A1LMNAMAPTGAATDP1
SCHEMBL10891550 0.81 FFAR1 (0.59) CA12CA1CA2CA9ALDH1A1
SCHEMBL9480255 0.81 NR3C2 (0.70) CA12CA1CA2CA9ALDH1A1
SCHEMBL19119164 0.80 CA12 (1.00) CA12CA1CA2CA9ALDH1A1
SCHEMBL322990 0.80 CA12 (1.00) CA12CA1CA2CA9ALDH1A1
SCHEMBL9481726 0.79 NR3C2 (0.78) ALDH1A1LMNAMAPK1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210065-A A mixture of an aromatic amine, an oxidizer and an acid MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-05-11 US disclosed
EP-0479578-A1 Color-forming recording material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 EP disclosed