Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,5-Xylidine SCHEMBL11500767 | 0.86 | TDP1 (0.59) | MEN1KMT2ATP53TDP1THRB | |
| Propionic Acid SCHEMBL27538869 | 0.84 | TDP1 (0.45) | MEN1KMT2ATP53TDP1THRB | |
| Acetoacetic Acid SCHEMBL9480965 | 0.83 | CYP3A4 (0.43) | MEN1KMT2ATDP1THRBSMN1; SMN2 | |
| Acetoacetic Acid SCHEMBL11802765 | 0.81 | ALDH1A1 (0.46) | TDP1SMN1; SMN2CYP3A4HTTMAPT | |
| Acetoacetic Acid SCHEMBL11807528 | 0.80 | TSHR (0.71) | MEN1KMT2ATDP1CYP3A4ALOX15 | |
| O-Tolylamine SCHEMBL5679561 | 0.79 | CYP3A4 (0.54) | TDP1SMN1; SMN2CYP3A4MAPTALDH1A1 | |
| O-Tolylamine SCHEMBL11500268 | 0.79 | CYP3A4 (0.54) | TDP1SMN1; SMN2CYP3A4MAPTALDH1A1 | |
| Acetoacetic Acid SCHEMBL11500325 | 0.78 | ACHE (0.52) | MEN1KMT2ATDP1SMN1; SMN2CYP3A4 | |
| Methyl Alcohol SCHEMBL11681113 | 0.77 | TDP1 (0.59) | TP53TDP1THRBSMN1; SMN2CYP3A4 | |
| SCHEMBL33980 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243032-A | PREPARATION OF AZO PIGMENTS WITH LOW PCB CONTENT BY COUPLING IN THE PRESENCE OF OLEFINS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |