Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetoacetic Acid SCHEMBL11807425 | 0.85 | TSHR (0.57) | CYP3A4ABL1POLBNOS2ALDH1A1 | |
| Acetoacetic Acid SCHEMBL9480459 | 0.83 | MEN1 (0.42) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| Acetoacetic Acid SCHEMBL11666028 | 0.83 | ABL1 (0.44) | CYP3A4ABL1POLBNOS2ALDH1A1 | |
| Acetoacetic Acid SCHEMBL11059298 | 0.82 | TSHR (0.57) | CYP3A4ABL1POLBALDH1A1MEN1 | |
| Acetoacetic Acid SCHEMBL11499562 | 0.81 | ALDH1A1 (0.61) | CYP3A4ABL1NPSR1POLBALDH1A1 | |
| 4-Chloro-2-Nitroaniline SCHEMBL11802106 | 0.79 | LMNA (0.51) | CYP3A4POLBALDH1A1MEN1KMT2A | |
| SCHEMBL92153 | 0.78 | — | — | |
| 4-Chloroaniline SCHEMBL11070783 | 0.78 | MEN1 (0.46) | CYP3A4POLBALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL4146950 | 0.76 | CYP3A4 (0.62) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL131186 | 0.76 | CYP3A4 (0.62) | CYP3A4ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243032-A | PREPARATION OF AZO PIGMENTS WITH LOW PCB CONTENT BY COUPLING IN THE PRESENCE OF OLEFINS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
| US-4540776-A | Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4354968-A | Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4143033-A | WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |