Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544521 | 0.74 | EPHX1 (0.34) | DNM1ALDH1A1 | |
| SCHEMBL7443274 | 0.72 | ALDH1A1 (0.37) | DNM1ALDH1A1 | |
| SCHEMBL21038287 | 0.69 | — | — | |
| SCHEMBL30710203 | 0.68 | THRB (0.48) | DNM1ALDH1A1 | |
| SCHEMBL1472438 | 0.68 | THRB (0.48) | DNM1ALDH1A1 | |
| SCHEMBL12963165 | 0.67 | — | — | |
| SCHEMBL5771309 | 0.67 | — | — | |
| SCHEMBL2101563 | 0.67 | EPHX1 (0.41) | DNM1ALDH1A1 | |
| SCHEMBL12219410 | 0.66 | — | — | |
| SCHEMBL20145830 | 0.65 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247042-A | ISOTROPIC ACRYLIC POLYMER EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORP. | 1993-09-21 | — | — | US | disclosed |
| WO-1991003504-A1 | ACRYLIC POLYMERS EXHIBITING NONLINEAR OPTICAL RESPONSE | HOECHST CELANESE CORPORATION (US) | 1991-03-21 | — | — | WO | disclosed |