Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481067 | 0.96 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9638790 | 0.90 | MAPT (0.49) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| Nitric Acid SCHEMBL9638527 | 0.86 | MAPT (0.47) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9480370 | 0.78 | MAPT (0.43) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9637744 | 0.76 | MAPT (0.68) | ALDH1A1MAPTKMT2AGAATDP1 | |
| SCHEMBL9688028 | 0.74 | MAPT (0.44) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9638422 | 0.74 | MAPT (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL9483397 | 0.73 | MAPT (0.55) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL10580564 | 0.73 | RAB9A (0.43) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL8412603 | 0.72 | KMT2A (0.41) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194659-A | High melting amino aromatic nitrate esters | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-03-16 | — | — | US | disclosed |