Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687117 | 0.85 | RAB9A (0.47) | MAPTKMT2AMEN1POLBGSK3A | |
| SCHEMBL11969793 | 0.78 | KMT2A (0.47) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27984414 | 0.77 | MAPT (0.42) | MAPTKMT2AMEN1POLBGSK3A | |
| SCHEMBL9807546 | 0.75 | MAPT (0.51) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6672241 | 0.74 | MAPT (0.41) | MAPTKMT2AMEN1POLBGSK3A | |
| SCHEMBL9638790 | 0.74 | MAPT (0.49) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9481067 | 0.74 | ALDH1A1 (0.46) | MAPTKMT2AMEN1POLBGSK3A | |
| SCHEMBL9480960 | 0.74 | ALDH1A1 (0.46) | MAPTKMT2AMEN1POLBGSK3A | |
| SCHEMBL28813961 | 0.72 | MAPT (0.39) | MAPTKMT2AMEN1POLBGSK3A | |
| SCHEMBL9637744 | 0.72 | MAPT (0.68) | MAPTKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5163970-A | NITRO-P-PHENYLENEDIAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COLORING AGENTS CONTAINING THESE FOR USE ON KERATIN FIBRES | HANS SCHWARZKOPF GMBH (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5067967-A | Nitro dyes for oxidation color dyes | 501 HANS SCHWARZKOPF GMBH (DE) | 1991-11-26 | — | — | US | disclosed |