Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480969 | 1.00 | LMNA (0.47) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| SCHEMBL9481824 | 0.73 | LMNA (0.37) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| SCHEMBL9481826 | 0.73 | LMNA (0.37) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| SCHEMBL27382017 | 0.71 | L3MBTL1 (0.48) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| SCHEMBL9481177 | 0.70 | L3MBTL1 (0.56) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| SCHEMBL9482008 | 0.70 | ALDH1A1 (0.49) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| SCHEMBL9482012 | 0.70 | ALDH1A1 (0.49) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10804571 | 0.69 | L3MBTL1 (0.55) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| Bromide SCHEMBL10804901 | 0.69 | L3MBTL1 (0.55) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10805251 | 0.69 | ALDH1A1 (0.48) | LMNASMN1; SMN2POLBMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240918-A | Analgesics | EGIS GYOGYSZERGYAR (HU) | 1993-08-31 | — | — | US | disclosed |