Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.51 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318061 | 0.85 | LMNA (0.49) | LMNAOPRM1OPRL1OGFRL1KMT2A | |
| SCHEMBL6238822 | 0.85 | KMT2A (0.51) | LMNAOPRM1OPRL1OGFRL1KMT2A | |
| SCHEMBL31171169 | 0.83 | MAPKAPK2 (0.49) | OPRM1OGFRL1KDM4EMAPKAPK2ALDH1A1 | |
| SCHEMBL9685713 | 0.82 | KMT2A (0.62) | LMNAOPRM1OPRL1OGFRL1KMT2A | |
| SCHEMBL10617106 | 0.82 | KMT2A (0.51) | LMNAOPRM1OPRL1OGFRL1KMT2A | |
| SCHEMBL6245939 | 0.80 | MAPKAPK2 (0.54) | LMNAKDM4EMAPKAPK2TSHRALDH1A1 | |
| SCHEMBL12592476 | 0.79 | LMNA (0.60) | LMNAOPRM1OPRL1OGFRL1KMT2A | |
| Hydrochloric Acid SCHEMBL6354640 | 0.79 | MAPKAPK2 (0.53) | LMNAKMT2AKDM4EMAPKAPK2TSHR | |
| SCHEMBL10484393 | 0.79 | KMT2A (0.50) | LMNAOPRM1OPRL1OGFRL1KMT2A | |
| SCHEMBL274568 | 0.77 | OPRM1 (0.60) | LMNAOPRM1OPRL1OGFRL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303148-B | 1-substituted beta-carboline derivatives and application thereof | 南京农业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111303148-A | 1-substituted β -carboline derivatives and application thereof | 南京农业大学 | 2020-06-19 | — | — | CN | disclosed |
| US-5256533-A | Preincubating sample with an alpha-2-inhibitor; comparing fluorescence in test to control tissues | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 1993-10-26 | — | — | US | disclosed |
| WO-1991014184-A1 | BETA CARBOLINES AS VITAL STAINS FOR NEUROTRANSMITTER SYSTEMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-09-19 | — | — | WO | disclosed |