Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 9/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9480994 | 0.99 | HRH3 (0.46) | HRH3UBE2MDCUN1D1APPKDM4E | |
| SCHEMBL9481084 | 0.94 | HRH3 (0.49) | HRH3UBE2MDCUN1D1APPKDM4E | |
| SCHEMBL9481058 | 0.90 | HRH3 (0.51) | HRH3UBE2MDCUN1D1APPKDM4E | |
| SCHEMBL9482297 | 0.88 | HRH3 (0.51) | HRH3UBE2MDCUN1D1APPKDM4E | |
| Hydrochloric Acid SCHEMBL9481001 | 0.87 | HRH3 (0.50) | HRH3UBE2MDCUN1D1APPKDM4E | |
| SCHEMBL9480688 | 0.83 | UBE2M (0.53) | HRH3UBE2MDCUN1D1 | |
| SCHEMBL9481024 | 0.81 | HRH3 (0.46) | HRH3UBE2MDCUN1D1APPKDM4E | |
| SCHEMBL9480735 | 0.80 | HRH3 (0.46) | HRH3UBE2MDCUN1D1APPKDM4E | |
| SCHEMBL9481451 | 0.79 | DCUN1D1 (0.49) | HRH3UBE2MDCUN1D1RAD52 | |
| SCHEMBL9481187 | 0.78 | OPRM1 (0.52) | HRH3UBE2MDCUN1D1APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216165-A | N-substituted aminoquinolines as analgesic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| US-5216165-A | N-substituted aminoquinolines as analgesic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |