Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.85 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.85 |
| ▸ | MMP2 | P08253 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.83 |
| ▸ | APEX1 | P27695 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.83 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.83 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.75 |
| ▸ | CNR1 | P21554 | 1/20 | 0.75 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.75 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481282 | 1.00 | APAF1 (0.85) | APAF1PSMD14MMP2TDP1APEX1 | |
| SCHEMBL9483126 | 0.93 | TDP1 (0.83) | APAF1PSMD14MMP2TDP1APEX1 | |
| SCHEMBL9483106 | 0.93 | TDP1 (0.83) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL27735290 | 0.92 | APAF1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL7718769 | 0.92 | APAF1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL7718771 | 0.92 | APAF1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL2283413 | 0.92 | APAF1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL28463175 | 0.92 | APAF1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL2063465 | 0.92 | APAF1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 | |
| Cefixime SCHEMBL3553111 | 0.91 | TDP1 (1.00) | APAF1PSMD14MMP2TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252731-A | Antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5110921-A | Bactericides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| US-4960889-A | CEPHALOSPORIN INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4731443-A | 7-acylamino-3-vinylcephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| EP-0244637-A1 | Starting compounds for 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-11-11 | — | — | EP | disclosed |
| EP-0030630-B1 | 7-ACYLAMINO-3-VINYLCEPHALOSPORANIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM; THEIR STARTING COMPOUNDS AND THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-01 | — | — | EP | disclosed |
| US-4585860-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| US-4487927-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| EP-0123024-A2 | 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |
| US-4423213-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-12-27 | — | — | US | disclosed |
| US-4409214-A | Including cefixime; antibiotics | FUJISAWA PHARMACEUTICAL, CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0030630-A2 | 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-24 | — | — | EP | disclosed |