SCHEMBL94823

SCHEMBL94823

Nc1nc(O)c2[nH]c(S)nc2n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481197 0.79 NUDT1 (0.35) NUDT1
8-Aminoguanine SCHEMBL27531531 0.79 PNP (0.48) NUDT1
SCHEMBL1766004 0.79 PDPK1 (0.44)
SCHEMBL16513146 0.76 NUDT1 (0.33) NUDT1
SCHEMBL9208925 0.76 DPP4 (0.35) NUDT1
SCHEMBL7618859 0.76 PRKACA (0.44) NUDT1
SCHEMBL1898084 0.76 NUDT1 (0.41) NUDT1
SCHEMBL27505859 0.72 ALDH1A1 (0.33) NUDT1
SCHEMBL887209 0.71 CYP1A2 (0.41)
SCHEMBL94915 0.68 ADORA2A (0.35) NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013090873-A1 A COMPOSITION AND METHOD FOR REDUCING CYANURIC ACID IN RECREATIONAL WATER HAVILAND PRODUCTS COMPANY (US) 2013-06-20 WO claimed
US-20050113520-A1 Halogenated styrene compounds and very low-loss polymers made therefrom ARNOUD OLIVIER (FR) 2005-05-26 US claimed
US-6891071-B2 Halogenated styrene compounds and very low-loss polymers made therefrom CORNING INCORPORATED (US) 2005-05-10 US claimed
US-20040077874-A1 Halogenated styrene compounds and very low-loss polymers made therefrom CORNING INCORPORATED 2004-04-22 US claimed
EP-1405849-A1 Halogenated styrene compounds and low-absorption-loss polymers obtainable therefrom Corning Incorporated (US) 2004-04-07 EP claimed
WO-2001073438-A1 RICIN INHIBITORS AND METHODS FOR USE THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 2001-10-04 WO claimed
EP-0515379-A4 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INC (US) 1994-09-14 EP claimed
EP-0515379-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1992-12-02 EP claimed
US-5094740-A TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED, INC. (US) 1992-03-10 US claimed
WO-1991012275-A1 TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
WO-1991012276-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
CN-108645832-B SERS chip and preparation method and application thereof 苏州英菲尼纳米科技有限公司 2021-07-27 CN disclosed
US-8680270-B2 Metallo-oxidoreductase inhibitors using metal binding moieties in combination with targeting moieties VIAMET PHARMACEUTICALS, INC. (US) 2014-03-25 US disclosed
EP-2086546-B1 METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES VIAMET PHARMACEUTICALS INC (US) 2013-07-10 EP disclosed
WO-2013090873-A1 A COMPOSITION AND METHOD FOR REDUCING CYANURIC ACID IN RECREATIONAL WATER HAVILAND PRODUCTS COMPANY (US) 2013-06-20 WO disclosed
US-5087337-A FLUORESCENT TAG FOR SUGAR ELECTROPHORESIS GLYCOMED, INC. (US) 1992-02-11 US disclosed
WO-1991012276-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1991-08-22 WO disclosed
WO-1991012275-A1 TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED INCORPORATED (US) 1991-08-22 WO disclosed
WO-1991012520-A1 FLUORESCENT TAG FOR SUGAR ELECTROPHORESIS GLYCOMED INCORPORATED (US) 1991-08-22 WO disclosed
US-3993661-A Quinone methide photograhpic reagent precursors POLAROID CORPORATION (US) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077874-A1 Halogenated styrene compounds and very low-loss polymers made therefrom AFF2, ETV6, MSH6 NUDT1 2957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.