Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607436 | 0.88 | ALDH1A1 (0.59) | BDKRB1LMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL14376040 | 0.87 | KDM4E (0.65) | BDKRB1LMNAKMT2AMAPTHTT | |
| SCHEMBL9484328 | 0.85 | BCAT2 (0.57) | BDKRB1LMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL248487 | 0.84 | RXFP1 (0.58) | BDKRB1LMNAKMT2AALDH1A1FLT1 | |
| SCHEMBL2525599 | 0.84 | RXFP1 (0.58) | BDKRB1LMNAKMT2AALDH1A1FLT1 | |
| SCHEMBL9468135 | 0.84 | PLK1 (0.54) | BDKRB1LMNAKMT2AHTTFLT1 | |
| SCHEMBL9484497 | 0.83 | ALDH1A1 (0.57) | BDKRB1LMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL28113465 | 0.82 | BDKRB1 (0.63) | BDKRB1LMNAKMT2AFLT1FLT4 | |
| SCHEMBL9468161 | 0.82 | FLT1 (0.52) | BDKRB1LMNAKMT2AALDH1A1HTT | |
| SCHEMBL9483252 | 0.81 | KMT2A (0.58) | BDKRB1LMNAKMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |