Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367478 | 0.81 | ALDH1A1 (0.42) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11323233 | 0.79 | GAA (0.52) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5375649 | 0.74 | TDP1 (0.57) | TDP1GPR35ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4321464 | 0.74 | S100A4 (0.53) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL65199 | 0.72 | TDP1 (0.61) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL17072807 | 0.71 | KMT2A (0.49) | TDP1GPR35ALDH1A1SMN1; SMN2S100A4 | |
| SCHEMBL2927806 | 0.71 | S100A4 (0.55) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2934864 | 0.71 | S100A4 (0.55) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL301228 | 0.71 | TDP1 (0.48) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3039191 | 0.71 | TDP1 (0.67) | TDP1GPR35TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210339-A | Nitrating agent, anhydride, clay, solvent | THE DOW CHEMICAL COMPANY (US) | 1993-05-11 | — | — | US | disclosed |