SCHEMBL9485271

SCHEMBL9485271

COC(=O)/C(Cl)=C(\Cl)C(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9485277 1.00 ALDH1A1 (0.35) ALDH1A1LMNA
SCHEMBL9720623 0.78 ALDH1A1 (0.45) ALDH1A1
SCHEMBL11145544 0.78 ALDH1A1 (0.45) ALDH1A1
SCHEMBL9720619 0.78 ALDH1A1 (0.45) ALDH1A1
SCHEMBL23829951 0.77 LMNA (0.32) LMNA
SCHEMBL9484837 0.75 ALDH1A1 (0.39) ALDH1A1LMNA
SCHEMBL9484834 0.75 ALDH1A1 (0.39) ALDH1A1LMNA
SCHEMBL9597506 0.73
SCHEMBL8571994 0.70
SCHEMBL11593610 0.70 ALDH1A1 (0.39) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210160-A PREPARATION OF HOMOPOLYMERS OF ETHENE AND COPOLYMERS OF ETHENE WITH HIGHER A-MONOOLEFINS USING A ZIEGLER CATALYST SYSTEM BASF AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
US-5112928-A Coordination catalysts containing aluminum, vanadium and transition metal compounds BASF AKTIENGESELLSCHAFT (DE) 1992-05-12 US disclosed
US-4831090-A Preparation of homopolymers of ethene and copolymers of ethene with higher α-monoolefins using a Ziegler catalyst system BASF AKTIENGESELLSCHAFT (DE) 1989-05-16 US disclosed
EP-0259124-A2 Method of polymerizing alpha olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-03-09 EP disclosed
US-4710552-A Preparation of homopolymers of ethene and copolymers of ethene with higherα-monolefins using a Ziegler catalyst system BASF AKTIENGESELLSCHAFT (DE) 1987-12-01 US disclosed