Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010648 | 0.90 | MEN1 (0.53) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL28230139 | 0.88 | CYP3A4 (0.55) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL28787263 | 0.86 | CYSLTR1 (0.52) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL8621924 | 0.84 | LMNA (0.50) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL6627563 | 0.82 | MEN1 (0.49) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL19745071 | 0.80 | MAOB (0.51) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL6089769 | 0.75 | CYSLTR1 (0.53) | ADAMTS4MEN1MAPTKMT2ACYSLTR1 | |
| SCHEMBL10858970 | 0.75 | CYP3A4 (0.56) | MAPTCYSLTR1CYSLTR2HDAC6CYP3A4 | |
| SCHEMBL27324326 | 0.75 | MEN1 (0.59) | MEN1MAPTKMT2ACYSLTR1CYSLTR2 | |
| SCHEMBL14763914 | 0.74 | CYP3A4 (0.48) | ADAMTS4MEN1KMT2ACYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185340-A | Angiotensin II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |