Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486675 | 0.89 | KCNH2 (0.52) | KCNH2POLBMEN1KMT2ALMNA | |
| SCHEMBL9485963 | 0.85 | KCNH2 (0.51) | KCNH2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9487166 | 0.84 | ALDH1A1 (0.51) | KCNH2POLBMEN1KMT2ALMNA | |
| SCHEMBL9486120 | 0.83 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL18395297 | 0.77 | KCNH2 (0.73) | KCNH2POLBMEN1KMT2ALMNA | |
| SCHEMBL9486050 | 0.76 | CNR2 (0.47) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL29464057 | 0.76 | EYA3 (0.65) | KCNH2LMNAHTTTDP1PTPN1 | |
| SCHEMBL282873 | 0.76 | EYA3 (0.65) | KCNH2LMNAHTTTDP1PTPN1 | |
| SCHEMBL17144952 | 0.75 | KCNH2 (0.70) | KCNH2POLBMEN1KMT2ALMNA | |
| SCHEMBL9486236 | 0.75 | OXER1 (0.53) | MEN1KMT2ALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |