Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491249 | 0.93 | ACACB (0.34) | MAPTSMN1; SMN2HIF1AIDO1KMT2A | |
| SCHEMBL9491241 | 0.93 | ACACB (0.34) | MAPTSMN1; SMN2HIF1AIDO1KMT2A | |
| SCHEMBL9485952 | 0.90 | RAB9A (0.33) | PDE4BIDO1NPSR1 | |
| SCHEMBL9487280 | 0.90 | RAB9A (0.37) | IDO1 | |
| SCHEMBL9486105 | 0.89 | RAB9A (0.36) | SMN1; SMN2 | |
| SCHEMBL9484845 | 0.88 | RAB9A (0.36) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9486170 | 0.88 | RAB9A (0.36) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9484754 | 0.88 | RAB9A (0.36) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9486091 | 0.88 | RAB9A (0.36) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9484886 | 0.88 | RAB9A (0.36) | MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |