Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434452 | 0.97 | ADRB2 (0.45) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Bromide SCHEMBL11242147 | 0.94 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL9860744 | 0.94 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL941546 | 0.94 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL28775567 | 0.88 | ADRB2 (0.39) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL7788981 | 0.86 | ADRB2 (0.38) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL27757907 | 0.82 | ADRB2 (0.39) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL28563877 | 0.82 | THRB (0.44) | TSHRCA1CA2THRB | |
| Acetic Acid SCHEMBL6871026 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1HPGDLMNAATM | |
| SCHEMBL588748 | 0.76 | CA1 (0.30) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258474-A | Process for producing α-olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-02 | — | — | US | disclosed |
| US-5215951-A | A solid catalyst component of titanium, magnesium, halogen and organosilicon; cocatalyst of sterically hindered aluminum amide; high activity | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0314169-A1 | Catalyst system and process for producing alpha-olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-03 | — | — | EP | disclosed |