SCHEMBL9486176

SCHEMBL9486176

Cc1cc(C)c(C)c(Sc2c(C)c(C)cc(C)c2C)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13386073 0.87 AR (0.35)
SCHEMBL9487527 0.87 CYP1A2 (0.30) TSHR
SCHEMBL9195027 0.80 CYP3A4 (0.32) CYP3A4TSHRMAPK1
SCHEMBL27475730 0.78 CYP3A4 (0.36) CYP3A4TSHRMAPK1
SCHEMBL9488176 0.77 RAPGEF4 (0.32)
SCHEMBL13915218 0.77 PRNP (0.39) CYP3A4MAPK1
SCHEMBL9486952 0.77 POLB (0.40)
SCHEMBL10810164 0.75 ALDH1A1 (0.36) CYP3A4
SCHEMBL120101 0.70 TSHR (0.39) CYP3A4TSHRMAPK1
SCHEMBL24305821 0.69 ALDH1A1 (0.42) CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7706658-B2 Copolymer and polymerizable composition FUJIFILM CORPORATION (JP) 2010-04-27 US disclosed
US-7706658-B2 Copolymer and polymerizable composition FUJIFILM CORPORATION (JP) 2010-04-27 US disclosed
US-20090116808-A1 COPOLYMER AND POLYMERIZABLE COMPOSITION FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
US-20090116808-A1 COPOLYMER AND POLYMERIZABLE COMPOSITION FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
EP-1565497-B1 OPTICAL MEMBERS AND COMPOSITIONS FOR PRODUCING THEM FUJIFILM CORP (JP) 2009-03-04 EP disclosed
US-20080139768-A1 Copolymer Having Cyclic Ether Structure in Main Chain, Optical Member Comprising the Copolymer, and Method of Producing the Same FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080139768-A1 Copolymer Having Cyclic Ether Structure in Main Chain, Optical Member Comprising the Copolymer, and Method of Producing the Same FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080124508-A1 Method For Producing Refractive Index Profile Plastic Optical Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
US-20080124508-A1 Method For Producing Refractive Index Profile Plastic Optical Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
US-7343073-B2 Optical members and compositions for producing them FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed
US-7343073-B2 Optical members and compositions for producing them FUJIFILM CORPORATION (JP) 2008-03-11 US disclosed
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed