Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486264 | 1.00 | LMNA (0.50) | LMNASMN1; SMN2POLBEGFRALDH1A1 | |
| SCHEMBL9041298 | 0.87 | LMNA (0.56) | LMNASMN1; SMN2POLBEGFRNPC1 | |
| SCHEMBL9041293 | 0.87 | LMNA (0.56) | LMNASMN1; SMN2POLBEGFRNPC1 | |
| SCHEMBL9486140 | 0.84 | P2RX7 (0.50) | POLBALDH1A1HPGDNPC1L3MBTL1 | |
| SCHEMBL9487168 | 0.82 | P2RX7 (0.36) | LMNASMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL7465180 | 0.80 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2POLBEGFRHPGD | |
| SCHEMBL203422 | 0.79 | HTR2C (0.38) | SMN1; SMN2POLBALDH1A1NPC1L3MBTL1 | |
| SCHEMBL9478389 | 0.79 | HTR2C (0.38) | SMN1; SMN2POLBALDH1A1NPC1L3MBTL1 | |
| SCHEMBL29359186 | 0.79 | HTR2C (0.38) | SMN1; SMN2POLBALDH1A1NPC1L3MBTL1 | |
| SCHEMBL31289589 | 0.79 | HTR2C (0.38) | SMN1; SMN2POLBALDH1A1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039810-A | Pyridyl propenoate compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-08-13 | — | — | US | claimed |
| JP-1132565-A | — | — | None | — | — | JP | disclosed |
| US-5198444-A | Methyl α-(2-substituted)pyrid-3-yl-β-methoxyacrylates, compositions containing them and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5158954-A | For agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-27 | — | — | US | disclosed |
| US-5039810-A | Pyridyl propenoate compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5039810-A | Pyridyl propenoate compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5008276-A | Plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-16 | — | — | US | disclosed |
| JP-H01132565-A | PRODUCTION OF PROPENOIC ACID DERIVATIVE | IMPERIAL CHEM IND PLC <ICI> | 1989-05-25 | — | — | JP | disclosed |
| EP-0312243-A2 | Methyl 2-[2-(3-substituted phenoxy)pyridin-3-yl]-3-methoxypropenoatesand their use as fungicides | ZENECA LIMITED (GB) | 1989-04-19 | — | — | EP | disclosed |