Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278966 | 0.84 | ACHE (0.50) | ALDH1A1SMN1; SMN2KMT2AHPGDACHE | |
| SCHEMBL9486947 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPSR1KMT2AACHE | |
| SCHEMBL13317304 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPSR1KMT2AMAPT | |
| SCHEMBL5608623 | 0.81 | SLC6A4 (0.47) | SMN1; SMN2KMT2AMAPTHPGDACHE | |
| SCHEMBL822665 | 0.81 | TSHR (0.50) | ALDH1A1SMN1; SMN2KMT2AHPGDACHE | |
| SCHEMBL30695769 | 0.81 | TSHR (0.50) | ALDH1A1SMN1; SMN2KMT2AHPGDACHE | |
| SCHEMBL5608759 | 0.79 | GAA (0.55) | ALDH1A1SMN1; SMN2KMT2AHPGDACHE | |
| SCHEMBL5340839 | 0.78 | NPSR1 (0.59) | ALDH1A1SMN1; SMN2NPSR1KMT2AMAPT | |
| SCHEMBL14021979 | 0.78 | KMT2A (0.44) | SMN1; SMN2KMT2AACHETSHRTDP1 | |
| SCHEMBL9501792 | 0.78 | KMT2A (0.41) | ALDH1A1KMT2AMAPTACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |