Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090838 | 0.85 | SLC6A4 (0.40) | SLC6A4TDP1GAAACHETEAD4 | |
| SCHEMBL5608759 | 0.82 | GAA (0.55) | KMT2ATDP1GAAACHELMNA | |
| SCHEMBL6150468 | 0.81 | KMT2A (0.48) | KMT2ASLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL5545716 | 0.80 | ALDH1A1 (0.44) | KMT2ASLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL5608623 | 0.80 | SLC6A4 (0.47) | KMT2ASLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL30695769 | 0.80 | TSHR (0.50) | KMT2ATDP1GAATSHRACHE | |
| SCHEMBL822665 | 0.80 | TSHR (0.50) | KMT2ATDP1GAATSHRACHE | |
| SCHEMBL3278966 | 0.79 | ACHE (0.50) | KMT2ATDP1GAATSHRACHE | |
| SCHEMBL9487542 | 0.78 | ALDH1A1 (0.47) | KMT2ATDP1GAATSHRACHE | |
| SCHEMBL14586639 | 0.78 | AR (0.51) | KMT2ASLC6A4TDP1ACHETEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |