Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.57 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846245 | 0.84 | GAA (0.68) | GAAFFAR1L3MBTL1ALDH1A1HTT | |
| SCHEMBL9565619 | 0.79 | KDM4E (0.51) | GAAFFAR1SQORMAPK14L3MBTL1 | |
| SCHEMBL9487664 | 0.78 | KDM4E (0.50) | FFAR1MAPK14L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9488463 | 0.78 | KDM4E (0.50) | FFAR1SQORMAPK14L3MBTL1MEN1 | |
| SCHEMBL18292395 | 0.77 | ACP1 (0.55) | FFAR1L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL29638126 | 0.75 | TGFBR1 (0.57) | SQORMAPK14L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1358217 | 0.75 | TGFBR1 (0.57) | SQORMAPK14L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL19882071 | 0.73 | KDM4E (0.65) | MAPK14L3MBTL1ALDH1A1MEN1HTT | |
| SCHEMBL6819027 | 0.73 | ALDH1A1 (0.71) | SQORL3MBTL1ALDH1A1KDM4ETDP1 | |
| SCHEMBL29728520 | 0.73 | TGFBR1 (0.56) | SQORMAPK14L3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3251581-A | — | — | None | — | — | JP | disclosed |
| US-5250533-A | Fungicidal pyridinylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| JP-H03251581-A | PYRIDINYLPYRIMIDINE DERIVATIVE | BAYER AG | 1991-11-11 | — | — | JP | disclosed |
| EP-0431424-A2 | Pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |