Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 10/20 | 0.45 |
| ▸ | HTR3A | P46098 | 10/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823896 | 0.89 | HSD17B10 (0.58) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL2728633 | 0.89 | HSD17B10 (0.58) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL13057071 | 0.87 | HTR1A (0.57) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL9487144 | 0.86 | MAPT (0.44) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL576094 | 0.83 | ACHE (0.53) | HTR1AHTR3AARCYP1A2CYP3A4 | |
| SCHEMBL9488946 | 0.83 | HTR1A (0.45) | MAPTMEN1KMT2ALMNATP53 | |
| Hydrogen Sulfide SCHEMBL11580912 | 0.81 | HTR1A (0.50) | HTR1AHTR3AARCYP1A2CYP3A4 | |
| SCHEMBL15906499 | 0.81 | HTR1A (0.50) | HTR1AHTR3AARCYP1A2CYP3A4 | |
| SCHEMBL29031117 | 0.81 | HTR1A (0.55) | HPGDHTR1AHTR3AARSLC6A4 | |
| Phosphine SCHEMBL29157942 | 0.81 | HTR1A (0.50) | HTR1AHTR3AARCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |