Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258673 | 0.89 | GABRA1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL169506 | 0.89 | GABRA1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9488152 | 0.88 | SHBG (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Methylamine SCHEMBL27931104 | 0.87 | GABRA1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL7055042 | 0.87 | GABRA1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL150658 | 0.87 | GABRA1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21267257 | 0.86 | CHRM2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| Formamide SCHEMBL27885905 | 0.84 | GABRA1 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18251575 | 0.83 | HTR2A (0.41) | CYP3A4TAAR1ALDH1A1CHRM2 | |
| Diethylamine SCHEMBL8994091 | 0.83 | CHRM2 (0.48) | GABRA1GABRB2TAAR1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6926949-B1 | Heat-activatable modular structural member, its use and process for the direct glazing of vehicles and adhesive therefor | ESSEX SPECIALTY PRODUCTS, INC. (US) | 2005-08-09 | — | — | US | disclosed |
| US-6001204-A | APPLYING IN SOFT STATE ALONG EDGE OF MODULAR COMPONENT PROFILED STRIP OF LATENT REACTIVE ADHESIVE; ALLOWING PORTION OF ADHESIVE TO HARDEN; CONTACTING WITH SECOND MOLDULE TO BE GLUED; PRESSING TO SOLIDIFY ADHESIVE | ESSEX SPECIALITY PRODUCTS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0638099-A1 | THERMALLY ACTIVATABLE MODULAR CONSTRUCTION ELEMENT, ITS USE, DIRECT GLAZING PROCESS FOR VEHICLES, AND ADHESIVE | Gurit-Essex AG (CH) | 1995-02-15 | — | — | EP | disclosed |