SCHEMBL9064360

SCHEMBL9064360

Cc1cc(C)c(C)c(Oc2c(C)c(C)cc(C)c2C)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488797 0.87 TDP2 (0.34) TSHR
SCHEMBL14802289 0.84 ALDH1A1 (0.35) CYP3A4
SCHEMBL10777137 0.80 CYP3A4 (0.32) CYP3A4TSHRMAPK1
SCHEMBL5566891 0.78 ACHE (0.43) CYP3A4MAPK1
SCHEMBL12141654 0.78 CYP3A4 (0.42) CYP3A4MAPK1
SCHEMBL9488169 0.77 LTA4H (0.48) TSHRMAPK1
SCHEMBL9488967 0.77 ALDH1A1 (0.42) MAPK1
SCHEMBL10629501 0.76 ALDH1A1 (0.41) CYP3A4TSHR
SCHEMBL10304840 0.75 LMNA (0.32)
SCHEMBL11026412 0.75 ACHE (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067643-B2 Sulphonium salt initiators BASF SE (DE) 2011-11-29 US disclosed
US-20090197987-A1 Sulphonium Salt Initiators IGM GROUP B.V. (NL) 2009-08-06 US disclosed
EP-0408901-B1 Process for the preparation of expandable beads ENICHEM SPA (IT) 1996-04-24 EP disclosed
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
WO-1992002579-A1 USE OF PHOSPHOROUSTRISLACTAMS AS COMPATIBILIZING AGENTS FOR POLYPHENYLENE OXIDE/POLYESTER BLENDS ALLIED-SIGNAL INC. (US) 1992-02-20 WO disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed
EP-0436136-A1 Compatibilized polyphenylene ehter resin/nylon resin blends containing aromatic phosphorous-containing compounds GENERAL ELECTRIC COMPANY (US) 1991-07-10 EP disclosed
EP-0408901-A2 Process for the preparation of expandable beads ENICHEM S.p.A. (IT) 1991-01-23 EP disclosed
EP-0185054-A1 GEN ELECTRIC 1986-06-25 EP disclosed
WO-1985005372-A1 MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS AND PROCESS GENERAL ELECTRIC COMPANY (US) 1985-12-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197987-A1 Sulphonium Salt Initiators LIFR, LUC7L2, LBR CYP3A4 4339/4885TSHR 982/4885MAPK1 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.