SCHEMBL3331237

SCHEMBL3331237

Cc1cc(Oc2ccccc2)c(C)c(C)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.44
TSHR P16473 1/20 0.44
TTR P02766 4/20 0.42
BRD4 O60885 1/20 0.41
RIPK1 Q13546 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
NTRK1 P04629 1/20 0.38
IGF1R P08069 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488025 0.82 LTA4H (0.42) LTA4HTSHRTTRBRD4RIPK1
SCHEMBL8736795 0.81 LTA4H (0.46) LTA4HTSHRTTRRIPK1SLC6A2
SCHEMBL28926763 0.80 TTR (0.44) LTA4HTSHRTTRBRD4CYP1A2
SCHEMBL10006897 0.80 LTA4H (0.55) LTA4HTSHRTTRRIPK1SLC6A2
SCHEMBL7935634 0.79 ACHE (0.31) ALDH1A1GAAKMT2A
SCHEMBL4819119 0.79 TTR (0.42) LTA4HTSHRTTRALDH1A1
SCHEMBL9488169 0.78 LTA4H (0.48) LTA4HTSHRCYP1A2CYP2C9CYP2C19
SCHEMBL11579139 0.77 LTA4H (0.44) LTA4HTSHRTTRBRD4ALDH1A1
SCHEMBL12925863 0.76 LTA4H (0.57) LTA4HTSHRHTTL3MBTL1KMT2A
SCHEMBL27109839 0.75 SLC6A4 (0.45) LTA4HTSHRTTRRIPK1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349218-A2 Separation of 3,3,',4,4'- and 2,3,3',4'-tetramethyldiphenyl ether AMOCO CORPORATION (US) 1990-01-03 EP claimed
JP-56057796-A None JP disclosed
CN-115536627-B Preparation method of diphenyl ether tetracarboxylic dianhydride 天津众泰材料科技有限公司 2024-01-26 CN disclosed
CN-115536627-A Preparation method of diphenyl ether tetracid dianhydride 天津众泰材料科技有限公司 2022-12-30 CN disclosed
CN-111349065-B Preparation method of 3,3',4,4' -diphenyl ether tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2022-08-30 CN disclosed
CN-111187240-B Preparation method of 4, 4-diphenyl ether dianhydride 河北海力香料股份有限公司 2021-12-07 CN disclosed
CN-111349065-A Preparation method of 3,3',4,4' -diphenyl ether tetracarboxylic dianhydride 大连新阳光材料科技有限公司 2020-06-30 CN disclosed
CN-111187240-A Preparation method of 4, 4-diphenyl ether dianhydride 河北海力香料股份有限公司 2020-05-22 CN disclosed
JP-2010189295-A METHOD FOR PRODUCING DIPHENYLETHER TETRACARBOXYLIC DIANHYDRIDE AIR WATER INC 2010-09-02 JP disclosed
US-20080281073-A1 High-Purity Oxydiphthalic Acid Anhydride and Process for Producing the Same MITSUBISHI CHEMICAL CORPORATION (JP) 2008-11-13 US disclosed
WO-1989001935-A1 PROCESS FOR THE PREPARATION OF OXY-DIPHTHALIC ANHYDRIDES OCCIDENTAL CHEMICAL CORPORATION (US) 1989-03-09 WO disclosed
EP-0264624-A1 Process for the preparation of oxy-diphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1988-04-27 EP disclosed
EP-0154720-B1 POLYAMIC ACID COPOLYMER SOLUTIONS FOR IMPROVED SEMICONDUCTOR MANUFACTURING International Business Machines Corporation (US) 1988-03-02 EP disclosed
US-4697023-A HYDROXYLATION OF HALOPHTHALIC ANHYDRIDE, ETHERIFICATION OCCIDENTAL CHEMICAL CORPORATION (US) 1987-09-29 US disclosed
US-4590258-A HEAT SEALABLE COATINGS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1986-05-20 US disclosed
EP-0154720-A1 Polyamic acid copolymer solutions for improved semiconductor manufacturing International Business Machines Corporation (US) 1985-09-18 EP disclosed
JP-S5657796-A (TETRACARBOXYL-10-PHENYLPHENOXAPHOSPHINE-10-OXIDE) DIANHYDRIDE AND ITS PREPARATION YOKOYAMA MASAAKI 1981-05-20 JP disclosed
EP-0008735-A1 Process for the preparation of diphenyl ether carboxylic acids BAYER AG (DE) 1980-03-19 EP disclosed
US-4005102-A METHYLENE CHLORIDE, NITRIC AND SULFURIC ACIDS GENERAL ELECTRIC COMPANY (US) 1977-01-25 US disclosed
US-3981933-A SULFURIC ACID, NITRIC ACID, TOLUENE IN METHYLENE CHLORIDE GENERAL ELECTRIC COMPANY (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281073-A1 High-Purity Oxydiphthalic Acid Anhydride and Process for Producing the Same MAP1LC3C, MAP1LC3A, CYBA LTA4H 1215/4885TSHR 4535/4885TTR 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.