Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708933 | 0.93 | ACHE (0.46) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL29543680 | 0.93 | ACHE (0.58) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL29468631 | 0.93 | ACHE (0.58) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL575896 | 0.93 | ACHE (0.58) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL10710202 | 0.88 | ACHE (0.52) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL3894284 | 0.86 | ACHE (0.50) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL822376 | 0.84 | ACHE (0.48) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL31038384 | 0.84 | ACHE (0.48) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL11125164 | 0.84 | ACHE (0.48) | ACHEHTR1AHTR3ASMN1; SMN2IDO1 | |
| SCHEMBL4804097 | 0.83 | ALDH1A1 (0.43) | ACHEHTR1AHTR3ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |