Sugi Predict

Sugi Predict / Compounds / SCHEMBL9488308

SCHEMBL9488308

SCHEMBL9488308

CC(N)c1cccc(C2CCN(Cc3ccccc3)C2)c1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 4/20 0.54
▸ CCR5 P51681 4/20 0.47
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ TACR1 P25103 2/20 0.45
▸ HTR2A P28223 1/20 0.45
▸ HRH1 P35367 1/20 0.45
▸ ACHE P22303 1/20 0.44
▸ BACE1 P56817 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8844218 0.80 DRD2 (0.60) DRD2CCR5MEN1KMT2AACHE
SCHEMBL4204428 0.80 DRD2 (0.60) DRD2CCR5MEN1KMT2AACHE
SCHEMBL4204422 0.80 DRD2 (0.60) DRD2CCR5MEN1KMT2AACHE
SCHEMBL22755777 0.79 MEN1 (0.68) DRD2CCR5MEN1KMT2AACHE
SCHEMBL3598146 0.79 MEN1 (0.68) DRD2CCR5MEN1KMT2AACHE
SCHEMBL6023725 0.79 MEN1 (0.68) DRD2CCR5MEN1KMT2AACHE
SCHEMBL24240460 0.78 MEN1 (0.55) DRD2CCR5MEN1KMT2ATACR1
SCHEMBL16877167 0.78 CCR5 (0.67) DRD2CCR5MEN1KMT2AACHE
SCHEMBL9482766 0.78 DRD2 (0.54) DRD2CCR5MEN1KMT2A
SCHEMBL9542839 0.78 DRD2 (0.47) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5221676-A 7-substituted quinolones and naphthyridones as antibacterial agents WARNER-LAMBERT COMPANY (US) 1993-06-22 — — US disclosed