Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488308 | 0.78 | DRD2 (0.54) | DRD2 | |
| SCHEMBL15773064 | 0.76 | HTR2C (0.45) | SLC18A3 | |
| SCHEMBL22634030 | 0.74 | MGLL (0.48) | — | |
| SCHEMBL9482766 | 0.73 | DRD2 (0.54) | DRD2CHRM4SLC18A3 | |
| SCHEMBL8844262 | 0.72 | DRD2 (0.51) | DRD2CHRM4 | |
| SCHEMBL9542849 | 0.72 | ROCK2 (0.49) | DRD2CHRM4 | |
| SCHEMBL4204422 | 0.71 | DRD2 (0.60) | DRD2SLC18A3 | |
| SCHEMBL4204428 | 0.71 | DRD2 (0.60) | DRD2SLC18A3 | |
| SCHEMBL8844218 | 0.71 | DRD2 (0.60) | DRD2SLC18A3 | |
| SCHEMBL22928142 | 0.70 | DRD2 (0.62) | DRD2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016077-A1 | 7-SUBSTITUTED QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |