Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91974 | 0.92 | LTA4H (0.48) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL10027326 | 0.84 | NQO1 (0.50) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL3624247 | 0.82 | LTA4H (0.47) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL13918745 | 0.82 | ALDH1A1 (0.55) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL12963416 | 0.82 | ALDH1A1 (0.55) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL14489702 | 0.82 | ELANE (0.49) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL9487763 | 0.81 | KMT2A (0.58) | LTA4HKMT2A | |
| SCHEMBL2256145 | 0.80 | LTA4H (0.41) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL13347816 | 0.80 | LTA4H (0.45) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL2004550 | 0.80 | LTA4H (0.55) | LTA4HPLA2G2AKMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |