Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271649 | 0.88 | PLA2G2A (0.47) | LTA4HPLA2G2ACA12CA1CA2 | |
| SCHEMBL91974 | 0.87 | LTA4H (0.48) | LTA4HPLA2G2AKMT2ACA12CA1 | |
| SCHEMBL5266313 | 0.86 | PLA2G2A (0.55) | LTA4HPLA2G2AGPBAR1 | |
| SCHEMBL3237732 | 0.86 | KAT6A (0.39) | LTA4HKMT2ACA12CA1CA2 | |
| SCHEMBL5267874 | 0.85 | PLA2G2A (0.58) | LTA4HPLA2G2A | |
| SCHEMBL5273089 | 0.85 | PLA2G2A (0.58) | LTA4HPLA2G2A | |
| SCHEMBL5271277 | 0.85 | PLA2G2A (0.58) | LTA4HPLA2G2A | |
| SCHEMBL5268054 | 0.85 | PLA2G2A (0.58) | LTA4HPLA2G2A | |
| SCHEMBL5267532 | 0.85 | PLA2G2A (0.58) | LTA4HPLA2G2A | |
| SCHEMBL5267390 | 0.85 | PLA2G2A (0.58) | LTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363390-A1 | DERIVED LACTAM FROM D3 VITAMIN | Teijin Pharma Limited (JP) | 2011-09-07 | — | — | EP | disclosed |
| US-20110207944-A1 | VITAMIN D3 LACTAM DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |
| CN-1294129-C | Heteraryl-substituted porrole derivatives, their prep. and therapeutic use | SANKYO CO (JP) | 2007-01-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207944-A1 | VITAMIN D3 LACTAM DERIVATIVE | VDR, CYP24A1, CYP2R1 | LTA4H 114/4885PLA2G2A 2148/4885KMT2A 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.