SCHEMBL9488488

SCHEMBL9488488

COc1cc(OC)cc(Oc2cc(OC)cc(OC)c2)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.79
CYP1A1 P04798 7/20 0.55
CYP1B1 Q16678 7/20 0.55
CYP1A2 P05177 4/20 0.48
CYP3A4 P08684 3/20 0.48
CYP2E1 P05181 2/20 0.48
CYP2C8 P10632 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2A6 P11509 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP4B1 P13584 2/20 0.48
CYP2B6 P20813 2/20 0.48
CYP3A5 P20815 2/20 0.48
CYP2A7 P20853 2/20 0.48
CYP3A7 P24462 2/20 0.48
CYP2F1 P24903 2/20 0.48
CYP2C18 P33260 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2J2 P51589 2/20 0.48
CYP4F2 P78329 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3,5-Trimethoxybenzene SCHEMBL28493 0.89 ALDH1A1 (1.00) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
1,3,5-Trimethoxybenzene SCHEMBL28740008 0.85 ALDH1A1 (0.92) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
1,3,5-Trimethoxybenzene SCHEMBL28557531 0.85 ALDH1A1 (0.92) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
1,3,5-Trimethoxybenzene SCHEMBL28416912 0.85 ALDH1A1 (0.92) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL18415521 0.84 LTA4H (0.73) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL28356668 0.80 NQO2 (0.57) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL2752472 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL8864487 0.80 ALDH1A1 (0.65) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL22106546 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL2954516 0.79 ALDH1A1 (0.79) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1353103-A Functional dendritic molecular material and its preparing process UNIV FUDAN (CN) 2002-06-12 CN disclosed
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed