SCHEMBL8864487

SCHEMBL8864487

COc1cc(OC)cc(Oc2nc(Oc3cc(OC)cc(OC)c3)nc(Oc3cc(OC)cc(OC)c3)n2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.54
LMNA P02545 1/20 0.50
CYP1A1 P04798 8/20 0.44
CYP1B1 Q16678 8/20 0.44
RAB9A P51151 2/20 0.44
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HTT P42858 1/20 0.42
CYP1A2 P05177 4/20 0.39
CYP2E1 P05181 3/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2C8 P10632 3/20 0.39
CYP2D6 P10635 3/20 0.39
CYP2A6 P11509 3/20 0.39
CYP2C9 P11712 3/20 0.39
CYP4B1 P13584 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488488 0.80 ALDH1A1 (0.79) ALDH1A1CYP1A1CYP1B1SMN1; SMN2CYP1A2
SCHEMBL8864442 0.79 ALDH1A1 (1.00) ALDH1A1MEN1KMT2AL3MBTL1RAB9A
SCHEMBL8864653 0.77 TUBB4A (0.50) ALDH1A1MEN1KMT2AL3MBTL1LMNA
1,3,5-Trimethoxybenzene SCHEMBL28493 0.76 ALDH1A1 (1.00) ALDH1A1CYP1A1CYP1B1CYP1A2CYP2E1
SCHEMBL23999203 0.73 ALDH1A1 (0.86) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL9155278 0.70 ALDH1A1 (0.79) ALDH1A1MEN1KMT2AL3MBTL1RAB9A
SCHEMBL13955878 0.70 ALDH1A1 (0.46) ALDH1A1
1,3,5-Trimethoxybenzene SCHEMBL27603737 0.70 ALDH1A1 (0.85) ALDH1A1CYP1A1CYP1B1CYP1A2CYP2E1
SCHEMBL5198118 0.69 KMT2A (0.64) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL699439 0.69 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5667931-A THERMAL RESISTANCE, RESOLUTION, PHOTOSENSITIVITY KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 1997-09-16 US disclosed