SCHEMBL9488681

SCHEMBL9488681

CCc1cccc(Oc2cccc(CC)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 4/20 0.50
TDP1 Q9NUW8 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
SOD1 P00441 1/20 0.49
CYP1A2 P05177 1/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HSD17B10 Q99714 1/20 0.46
HTT P42858 1/20 0.46
TP53 P04637 1/20 0.46
IDO1 P14902 1/20 0.44
AGXT P21549 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
CETP P11597 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358275 1.00 ALDH1A1 (0.50) ALDH1A1KDM4ETDP1SMN1; SMN2SOD1
SCHEMBL5407250 0.94 KDM4E (0.58) ALDH1A1KDM4ETDP1SMN1; SMN2TSHR
SCHEMBL11736722 0.92 ALDH1A1 (0.53) ALDH1A1KDM4ETDP1SMN1; SMN2SOD1
SCHEMBL18415678 0.90 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1SMN1; SMN2SOD1
SCHEMBL920952 0.90 ST14 (0.48) ALDH1A1KDM4ETDP1SMN1; SMN2SOD1
SCHEMBL8243884 0.88 FFAR1 (0.51) ALDH1A1KDM4ETDP1SMN1; SMN2TSHR
SCHEMBL26218467 0.88 MAOB (0.60) ALDH1A1KDM4ETDP1SMN1; SMN2TSHR
SCHEMBL16301334 0.88 MAOB (0.46) ALDH1A1KDM4ETDP1SMN1; SMN2SOD1
SCHEMBL327459 0.88 KDM4E (0.62) ALDH1A1KDM4ETDP1SMN1; SMN2HTT
SCHEMBL16316325 0.88 SMN1; SMN2 (0.50) ALDH1A1KDM4ESMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
US-9908990-B2 Organic layer composition, organic layer, and method of forming patterns SAMSUNG SDI CO., LTD. (KR) 2018-03-06 US disclosed
US-9908990-B2 Organic layer composition, organic layer, and method of forming patterns SAMSUNG SDI CO., LTD. (KR) 2018-03-06 US disclosed
US-20160304700-A1 ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2016-10-20 US disclosed
US-20160304700-A1 ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2016-10-20 US disclosed
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed
EP-0135938-B1 PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES MITSUBISHI KASEI CORPORATION (JP) 1988-06-22 EP disclosed
US-4707536-A Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-11-17 US disclosed
US-4661581-A REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-28 US disclosed
EP-0135938-A2 Process for producing aromatic polyether ketones and polythioether ketones MITSUBISHI KASEI CORPORATION (JP) 1985-04-03 EP disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed