SCHEMBL920952

SCHEMBL920952

CCc1cccc(Oc2cccc(CN)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 1/20 0.48
MAOB P27338 2/20 0.47
LOXL2 Q9Y4K0 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
F10 P00742 2/20 0.45
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PNMT P11086 1/20 0.44
ENPP2 Q13822 1/20 0.44
SOD1 P00441 1/20 0.43
IDO1 P14902 1/20 0.42
AGXT P21549 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919982 0.93 ST14 (0.60) ST14MAOBTAAR1KDM4EALDH1A1
SCHEMBL923353 0.91 ST14 (0.58) ST14MAOBLOXL2TAAR1KDM4E
SCHEMBL9488681 0.90 ALDH1A1 (0.50) TAAR1KDM4EALDH1A1TDP1SMN1; SMN2
SCHEMBL4949955 0.90 ST14 (0.58) ST14MAOBLOXL2TAAR1F10
SCHEMBL30358275 0.90 ALDH1A1 (0.50) TAAR1KDM4EALDH1A1TDP1SMN1; SMN2
SCHEMBL5407250 0.84 KDM4E (0.58) MAOBKDM4EALDH1A1TDP1SMN1; SMN2
SCHEMBL1301847 0.84 LOXL2 (0.58) ST14MAOBLOXL2KDM4EALDH1A1
SCHEMBL920977 0.84 TP53 (0.53) ST14MAOBSMN1; SMN2
SCHEMBL284046 0.83 LOXL2 (0.55) LOXL2ALDH1A1SMN1; SMN2PNMTENPP2
SCHEMBL29906073 0.83 LOXL2 (0.55) LOXL2ALDH1A1SMN1; SMN2PNMTENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885MAOB 3730/4885LOXL2 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.