SCHEMBL11736722

SCHEMBL11736722

CCc1ccc(Oc2cccc(CC)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
KDM4E B2RXH2 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 1/20 0.49
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.45
MITF O75030 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
GFER P55789 1/20 0.45
KMT2A Q03164 1/20 0.45
NLRP1 Q9C000 1/20 0.45
NOD2 Q9HC29 1/20 0.45
ST14 Q9Y5Y6 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
TP53 P04637 1/20 0.44
FFAR1 O14842 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358275 0.92 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL9488681 0.92 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL919982 0.91 ST14 (0.60) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL5407250 0.90 KDM4E (0.58) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL9502073 0.89 ALDH1A1 (0.48) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL923353 0.89 ST14 (0.58) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL8243884 0.89 FFAR1 (0.51) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL327459 0.89 KDM4E (0.62) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL8429859 0.87 FDFT1 (0.46) ALDH1A1KDM4ESMN1; SMN2HTTTDP1
SCHEMBL8241107 0.87 ALDH1A1 (0.62) ALDH1A1KDM4ESMN1; SMN2HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed