Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 8/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351079 | 0.96 | ALDH1A1 (0.37) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| SCHEMBL5888492 | 0.78 | ALDH1A1 (0.41) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| Sulfuric Acid SCHEMBL7749074 | 0.78 | ALDH1A1 (0.47) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| Sulfuric Acid SCHEMBL8216715 | 0.78 | ALDH1A1 (0.42) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| Methanesulfonamide SCHEMBL9569316 | 0.77 | ALDH1A1 (0.44) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| Sulfuric Acid SCHEMBL11044859 | 0.77 | ALDH1A1 (0.46) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| Sulfuric Acid SCHEMBL9799185 | 0.76 | ALDH1A1 (0.41) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| SCHEMBL6018559 | 0.76 | ALDH1A1 (0.43) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| SCHEMBL8024990 | 0.75 | ALDH1A1 (0.37) | RECQLALDH1A1CYP3A4THRBALOX15 | |
| Sulfuric Acid SCHEMBL10429917 | 0.75 | ALDH1A1 (0.42) | RECQLALDH1A1CYP3A4THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280505-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-4865961-A | CYAN COUPLER | KONICA CORPORATION (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0280505-A2 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1988-08-31 | — | — | EP | disclosed |