Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709767 | 0.96 | ALDH1A1 (0.41) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Sulfuric Acid SCHEMBL7749074 | 0.91 | ALDH1A1 (0.47) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Methanesulfonamide SCHEMBL9569316 | 0.90 | ALDH1A1 (0.44) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Sulfuric Acid SCHEMBL11044859 | 0.90 | ALDH1A1 (0.46) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Sulfuric Acid SCHEMBL3453574 | 0.84 | ALDH1A1 (0.42) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| SCHEMBL11025440 | 0.84 | ALDH1A1 (0.44) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Methanesulfonamide SCHEMBL11294048 | 0.84 | ALDH1A1 (0.42) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Sulfuric Acid SCHEMBL11318250 | 0.83 | ALDH1A1 (0.41) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| Sulfuric Acid SCHEMBL7031463 | 0.83 | ALDH1A1 (0.41) | ALDH1A1THRBCYP3A4TDP1RECQL | |
| SCHEMBL6813401 | 0.82 | ALDH1A1 (0.52) | ALDH1A1THRBCYP3A4TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217643-B1 | METHOD FOR PROCESSING LIGHT-SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0384670-A2 | Method for processing light sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4745049-A | COLORFAST YELLOW COUPLERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-05-17 | — | — | US | disclosed |
| EP-0217643-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-04-08 | — | — | EP | disclosed |