Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350192 | 0.74 | ALDH1A1 (0.36) | TSHRL3MBTL1TDP1ALDH1A1ATM | |
| SCHEMBL4336336 | 0.70 | MEN1 (0.33) | TSHRL3MBTL1TDP1ALDH1A1ATM | |
| SCHEMBL6445704 | 0.70 | ALDH1A1 (0.33) | TSHRL3MBTL1TDP1ALDH1A1ATM | |
| SCHEMBL28550237 | 0.69 | NAAA (0.38) | TSHRALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL10591972 | 0.69 | NAAA (0.38) | TSHRALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL10595248 | 0.69 | NAAA (0.38) | TSHRALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL10592103 | 0.69 | NAAA (0.38) | TSHRALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL10595092 | 0.69 | NAAA (0.38) | TSHRALDH1A1MAPK1CYP3A4TP53 | |
| SCHEMBL8597513 | 0.69 | ALDH1A1 (0.36) | TSHRL3MBTL1TDP1ALDH1A1ATM | |
| SCHEMBL1451329 | 0.65 | PPM1B (0.31) | TSHRTDP1ALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251033-B1 | METATHESIS POLYMERIZATION OF CYCLOOLEFINS | HERCULES INCORPORATED (US) | 1993-03-03 | — | — | EP | disclosed |
| US-4900799-A | Metathesis polymerization of cycloolefins | TEIJIN LIMITED (JP) | 1990-02-13 | — | — | US | disclosed |
| EP-0251033-A2 | Metathesis polymerization of cycloolefins | HERCULES INCORPORATED (US) | 1988-01-07 | — | — | EP | disclosed |